Human Protein Kinase, DNA Activated, Catalytic Polypeptide (PRKDC) ELISA Kit

DNA-dependent protein kinase catalytic subunit (DNA-PKcs), encoded by the PRKDC gene, serves as the catalytic core of the DNA-PK holoenzyme. This Assay Genie ELISA Kit enables quantitative measurement of human PRKDC in research samples. As a serine/threonine kinase essential for non-homologous end joining (NHEJ) and V(D)J recombination, PRKDC plays a central role in DNA double-strand break repair, and its dysregulation is implicated in radiosensitivity, immunodeficiency, and oncology. The kit therefore supports DNA damage response research, radiosensitizer screening, and tumor biology studies.

This 96-assay colorimetric kit is intended for research use only and is validated for human tissue homogenates and related sample matrices. Reagents are supplied for a standard microplate workflow with absorbance readout on a plate reader, supporting studies of DNA repair capacity and PRKDC characterization in cell-derived or tumor tissue samples.