Human Protachykinin-1 (TAC1) ELISA Kit

A sandwich ELISA kit from Assay Genie for the quantitative detection of human Protachykinin-1 (TAC1), a secreted tachykinin-family neuropeptide that regulates pain transmission and inflammation. Dysregulation of protachykinin-1 has been implicated in conditions such as chronic pain, neuroinflammation, and psychiatric disorders, making it a valuable biomarker for research into those areas. The kit is reactive with human samples, including serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids, and shows specificity for natural and recombinant human Protachykinin-1.

The TAC1 gene encodes members of the tachykinin peptide hormone family, including substance P and neurokinin A, with four isoforms produced by alternative splicing; these peptides excite neurons, evoke behavioral responses, act as potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Reported performance characteristics include a detection range of 4.69-300pg/mL, a sensitivity of 2.1pg/mL, an intra-assay CV of 4.8%, and an inter-assay CV of 8.9%. For research use only.