Human Proprotein Convertase Subtilisin/Kexin Type 5 (PCSK5) ELISA Kit

PCSK5 is a member of the subtilisin-like proprotein convertase family that cleaves precursor proteins to generate bioactive hormones, growth factors, and neuropeptides. Researchers studying furin-dependent processing pathways, neuroendocrine signaling, and tissue-specific protease activity rely on quantitative measurement of PCSK5 levels across experimental models.

This Assay Genie ELISA Kit quantifies human PCSK5 in tissue homogenates and other sample types using an in vitro immunoassay workflow. The kit includes all reagents necessary for the assay: coated microplate, detection antibodies, standards, and substrate. Each kit supports 96 individual determinations, suitable for both pilot studies and larger screening campaigns.

Researchers commonly apply this kit in studies of proprotein processing in cancer cell lines and tumor tissue, neuroendocrine regulation and peptide hormone maturation, cardiovascular research examining PCSK5 expression in vascular tissue, metabolic pathways involving insulin precursor processing, and liver or kidney tissue analysis for convertase expression patterns.

Sample preparation typically involves homogenization of fresh or frozen tissue followed by dilution in assay buffer. The standard curve included in the kit allows conversion of absorbance readings to concentration values. The kit is intended for research use only and is not validated for diagnostic or therapeutic procedures.