Human Promyelocytic Leukemia Protein (PML) ELISA Kit

PML is the nuclear body scaffold tumor suppressor best known for its disruption by the t(15;17) translocation that produces the PML-RARA oncoprotein in acute promyelocytic leukemia, and it also coordinates DNA damage signaling, intrinsic antiviral responses, and apoptosis regulation. The Assay Genie Human Promyelocytic Leukemia Protein (PML) ELISA Kit quantitatively measures endogenous PML protein in human research specimens using a microplate immunoassay configured for 96 individual determinations per kit and validated for in vitro research use.

Recommended sample matrices include tissue homogenates and cell lysates, supporting work on PML nuclear body assembly, stress-triggered SUMO conjugation of PML, interferon-driven antiviral defense, and tumor suppressor crosstalk in oncology and cell biology studies. Each box contains reagents arranged across a standard microplate, with wells reserved for a standard curve and quality controls. Absorbance is read on a standard plate reader, and quantitative results are derived against the supplied reference standards.

Assay Genie provides this kit for research use only, aimed at laboratories investigating leukemia biology, viral host-pathogen interactions involving disruption of PML bodies by incoming pathogens, and the broader p53 and interferon signaling networks in which PML participates. Reagent handling, plate preparation steps, and recommended storage are detailed in the enclosed product insert supplied with the kit.