Human Programmed cell death 1 ligand 1 (CD274) ELISA Kit

Assay Genie offers a high-quality Sandwich ELISA Kit for the quantitative detection of human Programmed cell death 1 ligand 1 (CD274), also known as PD-L1. This colorimetric immunoassay is designed for the accurate measurement of CD274 in human serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids, with reactivity specific to human samples.

CD274 is a critical immune checkpoint protein that regulates the immune response in conditions such as cancer and autoimmune disorders, with its overexpression linked to immune evasion and poor prognosis in cancer patients. The kit is specific to natural and recombinant human Programmed cell death 1 ligand 1, making it a valuable tool for studies of immune regulation, biomarker research, and the development of targeted therapies.

Performance characteristics include a detection range of 0.312-20ng/mL and a sensitivity of 0.098ng/mL. Intra-assay precision is 4.0% CV and inter-assay precision is 7.8% CV. Recovery averages 98% (range 92-104%) for serum and 100% (range 94-106%) for plasma. The protein target is associated with UniProt entry Q9NZQ7, with a molecular weight of 20,454 Da. The kit is intended for research use only.