Human Profilin-2 (PFN2) ELISA Kit

Manufactured by Assay Genie, this ELISA kit is designed for the precise measurement of Profilin 2 (PFN2) levels in human serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. The assay uses a colorimetric detection method and is intended for research use only.

Reported performance specifications include a detection range of 0.625-40ng/mL, a sensitivity of 0.33ng/mL, an intra-assay CV of 5.1%, and an inter-assay CV of 9.3%. Recovery is given as an average of 103% (range 97-109%) for serum and 105% (range 99-111%) for plasma. Linearity has been evaluated in serum, EDTA plasma, and heparin plasma at dilutions of 1:2, 1:4, 1:8, and 1:16. The kit detects natural and recombinant human Profilin-2 (also known as Profilin II; UniProt P35080), a protein that binds actin and influences cytoskeletal structure. Dysregulation of Profilin 2 has been linked to diseases including cancer, neurological disorders, and autoimmune conditions, making it a relevant biomarker in biomolecular research.