Human Profilin 1 (PFN1) ELISA Kit

Quantitative measurement of human Profilin 1 (PFN1) protein levels is supported by this 96 assays research-use kit from Assay Genie, applicable to cell lysates, tissue homogenates, and similar sample matrices.

PFN1 is an actin-monomer binding protein that governs cytoskeletal dynamics, membrane trafficking, and phosphoinositide signaling through interactions with PIP2 and formin family proteins. Dysregulated profilin 1 expression and pathogenic variants in the PFN1 gene are investigated in amyotrophic lateral sclerosis (ALS) research, where specific mutations such as C71G and M114T are recognized contributors to motor neuron disease, and in cancer biology, where altered profilin activity influences tumor cell migration and metastatic behavior.

Each kit provides reagents sufficient for 96 assays on a microplate and supports in vitro research in neurodegeneration, oncology, cytoskeletal biology, and cell motility studies.