Human Proepiregulin (EREG) ELISA Kit

From Assay Genie, this Human Proepiregulin (EREG) ELISA Kit is a Sandwich-format immunoassay designed for the precise detection of proepiregulin levels in human samples. The kit is intended for research use only and is reactive with human samples, including serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

Quantitative performance specifications include a detection range of 15.6-1000pg/mL and a sensitivity of 10pg/mL. Precision is characterised by an intra-assay CV of 6.0% and an inter-assay CV of 10.5%. Linearity has been evaluated in serum, EDTA plasma and heparin plasma across 1:2, 1:4, 1:8 and 1:16 dilutions. Recovery averages are 113% for serum (range 107-119%) and 115% for plasma (range 109-120%). Specificity is demonstrated against natural and recombinant human Proepiregulin (UniProt O14944), a single-pass type I membrane protein with a molecular weight of 19,044 Da that functions as a ligand of the EGF receptor/EGFR and ERBB4, contributing to inflammation, wound healing, tissue repair, and oocyte maturation.