Human Procollagen II N-Terminal Propeptide (PIINP) ELISA Kit

A quantitative immunoassay from Assay Genie that measures Procollagen II N-Terminal Propeptide (PIINP) in human specimens, supporting research into cartilage collagen anabolism and joint tissue remodelling. Type II collagen is the dominant structural matrix component of hyaline cartilage, and circulating PIINP concentrations serve as an indicator of synthesis activity relevant to osteoarthritis progression, chondrocyte biology, growth plate development, and intervertebral disc studies.

The workflow accepts serum samples, plasma specimens, and tissue homogenate fractions, enabling translational projects that bridge clinical biobanks and in vivo model systems. Investigators studying rheumatoid arthritis, skeletal dysplasia, and cartilage repair strategies routinely track PIINP to assess anabolic versus catabolic balance.

Supplied as a complete kit with a pre-coated microplate, the protocol yields a chromogenic readout proportional to PIINP concentration in each well. Each pack provides reagents for 96 individual determinations, accompanied by a standard curve of known calibrators and a step-by-step procedure insert.