Human Procollagen I N-Terminal Propeptide (P1NP) ELISA Kit

Quantitative measurement of circulating procollagen I N-terminal propeptide (P1NP), the reference marker for type I collagen synthesis and bone formation, is enabled by this colorimetric microplate-format ELISA from Assay Genie. P1NP is widely used in clinical and translational research on osteoporosis, Paget’s disease of bone, fracture healing, and the monitoring of anabolic bone therapies such as teriparatide and romosozumab. The assay accepts human serum, citrated plasma, and EDTA plasma matrices, supporting longitudinal evaluation of osteoblast activity in patient cohorts and preclinical models. Each kit ships with all required buffers, lyophilized standards, precoated microplate strips, and detection antibody to run the full protocol from start to finish. Investigators studying bone turnover, age-related bone loss, glucocorticoid-induced osteoporosis, chronic kidney disease–mineral bone disorder, and metastatic bone disease rely on P1NP as a sensitive indicator of new collagen deposition. The kit is intended for research use only and should be run on a standard microplate reader capable of colorimetric readout. Reagent components should be kept refrigerated and protected from repeated freeze-thaw cycles to preserve antibody activity. One microplate provides enough wells for full standard curves, internal controls, and study samples.