Human PRICKLE1 ELISA Kit (HUFI07053)

The PRICKLE1 quantitative immunoassay from Assay Genie enables researchers to measure the planar cell polarity protein PRICKLE1 in human serum or plasma specimens. PRICKLE1 is a core component of the non-canonical Wnt/PCP signaling pathway and regulates cytoskeletal remodeling, neural tube closure, and directed cell migration during development. Loss-of-function mutations in the PRICKLE1 gene are linked to progressive myoclonus epilepsy (PME) and have been investigated in the context of neurodegeneration and seizure-related disorders.

This 96 Assays format kit is intended for in vitro research use only and supports studies into Wnt pathway dysregulation, planar cell polarity biology, and PRICKLE1-associated neurological disease. The assay accommodates work comparing patient cohorts carrying epilepsy-related PRICKLE1 variants against healthy controls, and provides a practical readout for labs profiling PCP signaling components in clinical and translational research samples.