Human Presenilin 2 (PS2) ELISA Kit

Brought to you by Assay Genie for neuroscience and neurodegeneration research, this kit enables quantitative measurement of Presenilin 2 (PSEN2), a catalytic subunit of the gamma-secretase complex that cleaves amyloid precursor protein to generate amyloid-beta peptides. Investigators studying familial early-onset Alzheimer's disease, including the N141I and M239V PSEN2 variants, use this assay to evaluate protein expression in brain tissue homogenates and cell lysates from human donors.

The plate-based format uses a human-specific antibody pair and is read on a standard microplate reader at an appropriate absorbance wavelength. A typical sample volume of 50 uL per well is recommended. Unopened kits are shipped refrigerated at 4°C; reconstituted standards and antibodies should be stored at -20°C and protected from light to maintain activity across limited freeze-thaw cycles. For research use only, not intended for clinical or diagnostic applications.