Human PRAM1 ELISA Kit (HUFI07055)

PML-RARA-regulated adaptor molecule 1 (PRAM1) operates as a cytoplasmic adaptor in granulocytes and monocytes, where it channels signals from activated integrins into downstream effector pathways that govern adhesion, chemotaxis, and oxidative burst. Assay Genie supplies this ELISA kit to enable quantitative measurement of PRAM1 in laboratory specimens, supporting research into acute promyelocytic leukemia biology, myeloid maturation, and innate immune regulation.

The assay uses a pre-coated microplate format with all critical reagents, including capture antibody, standards, detection antibody, and substrate, provided in dropper bottles sized for a complete plate run. Workflow proceeds through sequential incubation and wash steps readable on a standard plate reader, allowing parallel processing of experimental and standard samples. Researchers can apply the kit to studies of neutrophil activation, monocyte differentiation, or inflammation-related signal transduction.

Components should be refrigerated upon receipt and protected from light where indicated, with long-term storage following the temperatures listed on the vial labels and the certificate of analysis shipped with each lot. The kit is intended for research use only and has not been validated for diagnostic applications. Specificity testing confirms reactivity toward human PRAM1, with cross-reactivity information supplied in the product insert.