Human PPP1R13B (Apoptosis-stimulating of p53 protein 1) ELISA KIT (HUFI04948)

This solid-phase immunoassay from Assay Genie is configured for quantitative measurement of human PPP1R13B, the protein encoded by the PPP1R13B gene and widely known by its common alias ASPP1 (apoptosis-stimulating protein of p53, 1). ASPP1 is a member of the ASPP family of p53-binding partners: it docks onto the DNA-binding domain of p53 and selectively boosts transcription of pro-apoptotic target genes such as BAX, PUMA, and NOXA, while leaving p53's cell-cycle arrest program relatively untouched. The reagent set is supplied as a complete ELISA kit configured for 96 assays, intended for research use only, with reactivity restricted to human analytes and applicability to serum-derived or plasma-derived specimens in studies of p53 signaling, DNA damage responses, and tumor suppressor biology.