Human Potassium Chloride Cotransporters 2 (KCC2) ELISA Kit

Detect the neuronal chloride exporter KCC2 with this quantitative immunoassay from Assay Genie, built for neuroscience research laboratories studying inhibitory synaptic signaling. KCC2, encoded by the SLC12A5 gene, maintains low intracellular chloride in mature neurons and is essential for hyperpolarizing GABAergic transmission; downregulation or dysfunction of this transporter is implicated in epilepsy models, chronic pain states, neurodevelopmental disorders, and neurodegenerative disease research. The kit accepts a broad range of human-derived specimens, including tissue homogenates, cell lysates, and cell culture supernatants, supporting both in vitro and in vivo experimental contexts. Each kit provides reagents sufficient for 96 individual assays, run on standard microplate equipment with a colorimetric read-out suitable for batch processing. The assay is supplied for research use only.