Human POMP ELISA Kit (HUFI08607)

Assay Genie's quantitative immunoassay targets Proteasome Maturation Protein (POMP), the dedicated chaperone required for proteasome assembly in human cells. Also known as UMP1, POMP guides the folding and dimerization of alpha-ring intermediates before beta subunits are incorporated, and loss-of-function mutations in this gene are causally linked to proteasome-associated autoinflammatory syndromes such as PRAAS and CANDLE syndrome.

Accurate measurement of POMP supports research into proteasome biogenesis, immunoproteasome regulation, and the unfolded protein response. Investigators working on hematological malignancies and certain solid tumors — where proteasome activity is frequently dysregulated and drugs such as bortezomib and carfilzomib are deployed — use POMP quantification to track assembly dynamics. The complete kit is supplied in a 96 Assays format, intended for research use only, and supports in vitro studies in immunology, cell biology, and rare-disease mechanism research.