Human POMK (Protein O-mannose kinase) ELISA KIT (HUFI04947)

Assay Genie's human Protein O-mannose kinase immunoassay enables researchers to quantify POMK levels in human specimens, supporting studies into dystroglycanopathies and congenital muscular dystrophies. POMK is the kinase responsible for phosphorylating mannose residues on alpha-dystroglycan, a modification essential for laminin binding and basement membrane integrity. Loss-of-function variants in the POMK gene cause Walker-Warburg syndrome and limb-girdle muscular dystrophy, making this enzyme a key target for neuromuscular disease research. The assay is supplied as a complete microplate-based kit intended for in vitro research use only, providing all reagents needed for the specified batch of determinations. For optimal reagent stability, store the kit refrigerated, protect the substrate from light, and minimize freeze-thaw cycles by aliquoting working solutions. Allow plates and reagents to equilibrate to room temperature before initiating the protocol.