Human Polymerase DNA Directed Gamma 1 (POLg1) ELISA Kit

Mitochondrial DNA replication research benefits from quantitative measurement of POLg1, the catalytic subunit of DNA Polymerase Gamma, using this immunoassay from Assay Genie. POLg1 carries out mtDNA synthesis and repair, and altered expression is implicated in mitochondrial maintenance disorders including Alpers syndrome, progressive external ophthalmoplegia, and ataxia-neuropathy syndromes. Researchers investigating mtDNA copy number regulation, nucleoside reverse transcriptase inhibitor toxicity, and age-related mitochondrial decline use POLg1 quantification as a marker of mitochondrial biogenesis capacity.

The 96-assay kit accepts tissue homogenates and cell lysates, supporting workflows in neuroscience, myology, and cell biology laboratories focused on mitochondrial dysfunction. An absorbance-based readout is compatible with standard microplate readers. Kit components include a pre-coated plate, calibrators, and detection reagents for generating a standard curve and quantifying POLg1 protein in research samples. Intended for research use only; not for diagnostic or therapeutic procedures.