Human Polycystin-2 (PKD2) ELISA Kit

A high-quality sandwich ELISA from Assay Genie designed for the accurate, colorimetric detection of Polycystin-2 (PKD2) in human samples. The assay quantitatively measures Polycystin-2, a calcium-permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium, across serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. Intended for research use only, the kit supports studies into polycystic kidney disease, hypertension, and related conditions within the cardiovascular research area.

Reported performance characteristics include a detection range of 0.312–20 ng/mL and a sensitivity of 0.098 ng/mL, with an intra-assay CV of 4.3% and an inter-assay CV of 7.5%. The assay specifically recognises natural and recombinant human Polycystin-2 (UniProt Q13563), and shows average recovery of 96% (range 90–102%) in serum and 98% (range 92–104%) in plasma. Synonyms for the target protein include PC2, TRPP2, Polycystwin, and Polycystic kidney disease 2 protein.