Human POLR3B ELISA Kit (HUFI07120)

A solid-phase immunoassay from Assay Genie for quantitative measurement of POLR3B, the second-largest subunit of RNA polymerase III. This enzyme complex transcribes tRNAs, 5S ribosomal RNA, and other small non-coding RNAs in eukaryotic cells, and altered POLR3B expression has been implicated in POLR3-related leukodystrophy (4H syndrome) and Wiedemann-Rautenstrauch syndrome, a neonatal progeroid condition. Researchers use this kit to investigate RNA Polymerase III subunit biology, explore molecular mechanisms of rare neurological disorders, and screen for biomarkers associated with transcription-related disease pathways. Intended for research use only, the assay supports standard well-plate laboratory workflows and is supplied with the reagents needed for quantitative detection in human research samples.