Human PMS1 ELISA Kit (HUFI07153)

The Human PMS1 ELISA Kit from Assay Genie enables quantitative measurement of PMS1 (Postmeiotic Segregation Increased 1) protein, a core component of the DNA mismatch repair pathway that forms the MutLβ heterodimer with MLH1. The assay is specifically validated for detection of human PMS1 with species-validated antibodies that show no significant cross-reactivity against the related family members PMS2 or MLH3.

Researchers apply this microplate-based immunoassay to investigate MMR expression in tumor and matched normal tissue specimens, supporting studies of hereditary cancer syndromes such as Lynch syndrome and broader DNA repair mechanism research. Each plate delivers quantitative concentration values, allowing direct comparison of PMS1 levels across patient cohorts and treatment groups.

For research use only; not intended for diagnostic procedures. Store unopened reagents according to the supplied insert and avoid repeated freeze-thaw cycles of prepared working solutions to preserve antibody binding activity.