Human PML (Protein PML) ELISA Kit (HUFI07150)

PML (Promyelocytic Leukemia Protein) is a nuclear body organizer best known for its role as the fusion partner of RARA in acute promyelocytic leukemia, where the t(15;17) translocation produces the PML-RARA oncoprotein that disrupts normal myeloid differentiation.

This quantitative immunoassay from Assay Genie is configured for the in vitro measurement of human PML in serum or plasma-type research specimens, with an absorbance-based readout performed on a microplate platform and reagents supplied for 96 individual determinations.

The kit is intended for research use only, supporting investigations into PML nuclear body dynamics, interferon-driven antiviral responses, p53-associated tumor suppression pathways, and the post-translational sumoylation events that govern PML body assembly and disassembly.

Standard laboratory precautions apply: store unopened components refrigerated, allow plates and buffers to equilibrate to room temperature before use, and protect any light-sensitive reagents from prolonged exposure. Reconstituted standards and working solutions should be handled according to the insert, with repeated freeze-thaw cycles of protein-containing reagents avoided to preserve antigen binding activity.