Human PLEKHH2 ELISA Kit (HUFI07179)

PLEKHH2 (Pleckstrin Homology Domain Containing H2) encodes a cytoplasmic protein featuring tandem PH and MyTH4 domains that localizes to the renal podocyte foot process cytoskeleton. Variants in this gene have been associated with autosomal dominant focal segmental glomerulosclerosis and childhood-onset steroid-resistant nephrotic syndrome, making circulating levels of interest as a candidate biomarker for podocyte injury and proteinuria research. The Assay Genie kit quantifies endogenous target in clinical research specimens, with a pre-coated microplate, matched antibody pair, and calibrator set supplied for building a standard curve and deriving absolute concentration values. Following the immunoassay protocol, absorbance is recorded for quantitation against the included reference standards.