Human Platelet Activating Factor Acetylhydrolase 2 (PAFAH2) ELISA Kit

PAFAH2 is an intracellular serine hydrolase (~44 kDa subunit) that cleaves the acetyl group from the sn-2 position of platelet-activating factor (PAF), a potent phospholipid mediator of inflammation and anaphylaxis. Beyond PAF, the enzyme hydrolyzes oxidized phospholipids generated during oxidative stress, placing it at the intersection of redox biology and lipid peroxidation research. Published studies have linked PAFAH2 activity to cardiovascular pathophysiology, acute inflammatory responses, and cellular defenses against reactive oxygen species. Quantitative measurement in human plasma supports in vitro biomarker discovery and translational investigations in vascular biology, oxidative stress, and inflammation research using the Assay Genie platform.