Human Plasmalemma Vesicle Associated Protein (PLVAP) ELISA Kit

Forming the structural diaphragms of caveolae and fenestrae, plasmalemma vesicle associated protein (PLVAP), also designated PV-1, is an approximately 60 kDa endothelial transmembrane glycoprotein central to microvascular permeability. Dysregulation of this protein has been linked to blood-brain barrier breakdown, tumor angiogenesis, and diabetic microvascular complications. This Assay Genie ELISA-format immunoassay enables quantitative detection of human PLVAP across tissue homogenates, cell lysates, and other specimen preparations. The 96-assay configuration accommodates batch processing for multiple experimental conditions, treatment groups, or longitudinal time points, with reagents validated specifically for human reactivity. The kit supports in vitro and in vivo workflows in vascular biology, neuroscience, and oncology laboratories investigating endothelial barrier integrity and pathological angiogenesis.