Human Plakophilin 1 (PKP1) ELISA Kit

The Human Plakophilin 1 (PKP1) ELISA Kit from Assay Genie provides a quantitative immunoassay for measuring PKP1 protein in research samples. Plakophilin 1 is a key desmosomal plaque component that anchors intermediate filaments to cell-cell junctions in stratified epithelia, and it plays structural roles in keratinocyte adhesion, epidermal integrity, and hair follicle formation. Loss-of-function mutations in PKP1 cause ectodermal dysplasia-skin fragility syndrome, while reduced PKP1 expression has been reported in squamous cell carcinomas of the head, neck, and esophagus, making this protein a target of interest in dermatology and oncology research.

The kit supplies a pre-coated microplate, capture and detection antibodies, reference standards, and chromogenic substrate reagents for in vitro research workflows. Researchers apply this assay to profile PKP1 levels across epithelial tissue models, keratinocyte culture systems, and tumor-derived samples. Each kit contains sufficient reagents for a full microplate run and is intended for research use only, not for diagnostic procedures.