Human PKP3 (Plakophilin 3) ELISA Kit (HUFI07185)

The Assay Genie Plakophilin 3 ELISA Kit provides quantitative measurement of PKP3 in human samples, supporting research into desmosome assembly, epithelial barrier integrity, and tumor biomarker discovery. PKP3 is a cytoplasmic plaque protein of desmosomes that anchors keratin intermediate filaments at intercellular junctions, and altered PKP3 expression has been linked to arrhythmogenic right ventricular cardiomyopathy, certain pemphigus skin disorders, and carcinomas of colorectal, gastric, and lung origin.

This microplate immunoassay is used by investigators comparing circulating PKP3 levels across patient cohorts versus healthy controls, profiling matched tumor lysates against peripheral samples, and characterizing desmosome remodeling in cultured keratinocyte or cardiomyocyte monolayers. The kit includes a pre-coated strip plate, lyophilized recombinant standards, biotinylated detection antibody, streptavidin-HRP conjugate, concentrated wash buffer, chromogenic substrate, and stop solution. Reconstituted reagents are aliquoted and kept refrigerated to limit repeated freeze-thaw exposure, while unopened strips remain stable when stored dry and protected from light.