Human PITRM1 ELISA Kit (HUFI07193)

The Human PITRM1 ELISA Kit from Assay Genie enables quantitative measurement of pitrilysin metallopeptidase 1, a mitochondrial matrix metalloenzyme that processes and degrades mitochondrial targeting peptides. PITRM1 (also known as presequence protease, PreP) dysfunction has been implicated in neurodegenerative disease research, particularly Alzheimer's disease, where impaired intramitochondrial clearance of amyloid-beta peptides contributes to mitochondrial toxicity and cognitive decline.

Investigators studying mitochondrial proteostasis, amyloid-beta metabolism, and related neurological pathways can use this kit to measure PITRM1 concentrations in human clinical specimens. All reagents require refrigerated storage to preserve antibody activity, and the microplate-based format supports reliable batch processing of multiple samples per run. For research use only, the assay supports in vitro studies of mitochondrial function, peptide processing, and neurodegeneration mechanisms.