Human Phosphotyrosine ROR1 PharmaGenie ELISA Kit (SBRS1950)

Built to quantify the phosphorylated form of Receptor tyrosine kinase-like orphan receptor 1 (ROR1) in human cellular material, this Phosphorylation ELISA from Assay Genie gives researchers a targeted readout of receptor activation in cancer signaling studies. Each kit supports 96 individual reactions using cell lysates or tissue lysates, distinguishing phosphotyrosine ROR1 from total ROR1 protein.

ROR1 is normally expressed during embryonic development and is reactivated in several malignancies, including chronic lymphocytic leukemia and mantle cell lymphoma. Monitoring the phosphotyrosine residue specifically supports studies of upstream kinase activity, ligand-induced dimerization, and downstream pathway engagement in both cell-line models and primary patient samples.

Reagents are supplied for the microplate workflow, accommodating small pilot screens through larger comparative studies. For research use only. Valid comparisons across experiments depend on proper sample handling: snap-freeze tissues in liquid nitrogen immediately upon harvest, store lysates at -80°C, and include protease and phosphatase inhibitor cocktails during lysis to preserve the in vivo phosphorylation state.