Human Phosphotyrosine ErbB4 PharmaGenie ELISA Kit (SBRS1819)

The Human Phosphotyrosine ErbB4 PharmaGenie ELISA Kit from Assay Genie is a phosphorylation-specific immunoassay used in signal transduction research. ErbB4 (HER4) is a 180 kDa receptor tyrosine kinase of the EGFR/ErbB family, and quantifying its tyrosine phosphorylation state helps researchers monitor downstream signaling events triggered by ligands such as heregulin and HB-EGF.

The assay is validated specifically for detection of human ErbB4 phospho-tyrosine and is run on cell lysates and tissue lysates prepared with phosphatase inhibitor cocktails to preserve phospho-epitopes, making it relevant for studies in breast cancer, neurobiology, and cardiac development where ErbB4 plays context-dependent roles. Each kit contains a pre-coated microplate and is configured for 96 assays, supporting medium-throughput screening of pathway activation under different stimulation conditions, inhibitor treatments, or genetic perturbations. Recommended for in vitro research use only.