Human Phospholipase D3 (PLD3) ELISA Kit

Manufactured by Assay Genie, this Sandwich ELISA Kit is designed for the precise quantitative measurement of human Phospholipase D3 (PLD3) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay uses a colorimetric detection method and is specific for natural and recombinant human PLD3.

PLD3 is an essential enzyme involved in lipid metabolism and intracellular signaling pathways. Dysregulation of PLD3 has been linked to neurodegenerative diseases, Alzheimer's disease, and metabolic disorders, making this kit a valuable tool for researchers investigating disease mechanisms and potential therapeutic targets. The protein is a single-pass type II membrane protein located in the endoplasmic reticulum membrane, belongs to the phospholipase D family, and may be involved in APP processing.

Performance is reported with a detection range of 0.625-40ng/mL and a sensitivity of 0.31ng/mL. Precision is given as an intra-assay CV of 4.1% and inter-assay CV of 8.3%. Recovery is 97% (range 91-103%) for serum and 99% (range 93-105%) for plasma. Linearity has been validated in serum, EDTA plasma, and heparin plasma across dilutions from 1:2 to 1:16. For research use only.