Human Phospholipase A2 Receptor 1 (PLA2R1) ELISA Kit

Researchers studying autoimmune kidney disease recognise Phospholipase A2 Receptor 1 as the dominant podocyte autoantigen in primary membranous nephropathy, and the Assay Genie PLA2R1 immunoassay kit offers a 96-assay platform for quantifying the receptor protein in human specimens. The kit is supplied with a pre-coated plate, lyophilised recombinant standards, biotinylated detection reagent, enzyme conjugate, wash buffer, substrate solution, and stop reagent, and it is configured for in vitro work in immunology, nephrology, and glomerular-disease laboratories. PLA2R1 is a type I transmembrane glycoprotein of the mannose receptor family, expressed on glomerular podocytes, where it contributes to slit-diaphragm maintenance, receptor-mediated endocytosis, and interactions with circulating IgG4 autoantibodies. Applications supported by this format include serological profiling of membranous nephropathy cohorts, studies of antigen shedding from injured podocytes, complement activation pathway research, and glycan-dependent autoantibody binding analyses. Each batch is validated for human reactivity, the workflow fits standard plate-reader-based quantification, and the product is intended for research use only rather than diagnostic procedures.