Human Phospho-STAT2 (Y689) PharmaGenie ELISA Kit (SBRS1984)

This phosphorylation ELISA from Assay Genie quantitatively detects human STAT2 phosphorylated at tyrosine 689 (Y689), a modification that occurs rapidly upon type I interferon (IFN-α/β) stimulation and is required for ISGF3 complex assembly with STAT1 and IRF9. Researchers use the kit to monitor JAK-STAT pathway activation in cell lysates and tissue lysates, tracking downstream antiviral and immunomodulatory signaling. Capture antibodies are specific for the phosphorylated Y689 epitope, allowing discrimination between active and inactive STAT2 pools. The assay is supplied as a complete microplate-format kit intended for research use only; refrigerate the kit upon arrival, and avoid repeated freeze-thaw cycles of the standard and detection antibody. Applications include cytokine response studies, viral infection models, and compound screening for modulators of interferon signaling.