Human Phospho-PYK2 (Y402) PharmaGenie ELISA Kit (SBRS1941)

Researchers studying focal adhesion signaling can use this phosphorylation ELISA kit from Assay Genie to quantify the activated form of PYK2 (also known as PTK2B, RAFTK, or CAKβ) at its critical Y402 autophosphorylation site. Y402 phosphorylation is the principal activation marker for this non-receptor tyrosine kinase, equivalent to Y397 in focal adhesion kinase (FAK), and serves as a read-out of integrin-, calcium-, and Src-family-kinase-driven signaling cascades. The kit is validated for use with cell lysates and tissue lysates, making it applicable to cancer, cardiovascular, neuronal, and immune cell signaling studies where PYK2 activity contributes to adhesion, migration, proliferation, or survival outcomes. Supplied as a complete kit of reagents sufficient for 96 assays, the assay is suited to in vitro signaling research and pathway profiling in cell culture and tissue-based experiments. Standard storage at refrigerated temperatures preserves reagent activity across the kit's shelf life.