Human Phospho-ATR (T1989) and Total ATR PharmaGenie ELISA Kit (SBRS1756)

The ATR kinase, a roughly 301 kDa phosphoinositide 3-kinase-related enzyme, drives the replication-stress checkpoint, and threonine 1989 is the autophosphorylation site that marks its catalytically active state following DNA damage or replication fork stalling. This dual-analyte immunoassay from Assay Genie measures phospho-ATR (T1989) alongside total ATR from the same human cell lysate, enabling researchers to normalize pathway activation against total protein expression in DNA damage response, cell cycle, and chemo-sensitization studies. The 96-assay kit is intended for research use only and is read on standard microplate readers using absorbance-based detection.