Human Phosphatidylinositol Binding Clathrin Assembly Protein (PICALM) ELISA Kit

PICALM encodes a clathrin assembly protein critical for vesicle trafficking and receptor-mediated endocytosis at the plasma membrane. Investigators studying neurodegeneration frequently target PICALM because common polymorphisms in the gene are reproducibly associated with late-onset Alzheimer's disease susceptibility. This Assay Genie quantitative immunoassay enables measurement of endogenous human PICALM protein in tissue homogenates, cell lysates, and similar samples. The plate-based kit includes pre-coated capture wells, detection antibody, recombinant standard, and substrate reagents sufficient for 96 reactions. Unopened components should be stored refrigerated at 4 °C, while reconstituted standards require single-use aliquots held at -20 °C to preserve activity through repeated freeze-thaw cycles. Intended for research use only, the workflow supports biomarker discovery in neuroscience, hematology, and clathrin-mediated endocytosis research.