Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (PREX2) ELISA Kit

A sandwich ELISA kit from Assay Genie designed for the quantitative measurement of Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (PREX2) in human samples. The assay is intended for research use only and detects natural and recombinant human PREX2.

Compatible sample types include serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. The kit is supplied in a solid phase format, is recommended to be stored at -20°C, and is shipped at +4°C. PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP, with its activity synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G protein.

Performance characteristics quoted from the manufacturer's documentation include a detection range of 78-5000pg/mL, a sensitivity of 34pg/mL, an intra-assay CV of 3.9% and an inter-assay CV of 7.2%. The UniProt accession for the target protein is Q70Z35.