Human Phosphatase And Tensin Homolog (PTEN) ELISA Kit

This immunoassay kit from Assay Genie enables quantitative measurement of human PTEN protein, supporting cancer biology and signal transduction research where PTEN status is under investigation. PTEN acts as a lipid phosphatase that antagonizes PI3K signaling, and its frequent inactivation through mutation, deletion, or epigenetic silencing is a hallmark of prostate cancer, glioblastoma, endometrial carcinoma, breast cancer, and Cowden syndrome. Researchers can apply the kit to evaluate tumor suppressor expression in cell-based systems and tissue-derived preparations, including studies of drug response, pathway modulation, and disease progression.

Each kit is supplied with reagents to perform the assay in a microplate format, with protocols optimized for research use only. Components should be refrigerated upon arrival and handled according to standard laboratory practice. The workflow supports comparisons between healthy donor samples and disease-state specimens, evaluation of pharmacological agents that modulate PTEN expression, and characterization of cell lines engineered to perturb PTEN activity.

Applications extend across in vitro cell culture experiments, oncology biomarker screening projects, and translational investigations into metabolic and neurological conditions linked to PTEN dysfunction. The microplate-based workflow integrates with standard laboratory infrastructure and accommodates both small pilot studies and larger screening efforts in tumor suppressor biology and PI3K pathway research.