Human PHGDH ELISA Kit (HUFI07234)

A solid-phase ELISA from Assay Genie for quantifying human phosphoglycerate dehydrogenase (PHGDH) in research samples. PHGDH catalyzes the first committed step of the L-serine biosynthesis pathway, converting 3-phosphoglycerate to 3-phosphohydroxypyruvate, and has emerged as a focal point of cancer metabolism research, where elevated expression supports tumor growth and proliferation in breast cancer, melanoma, and certain lung tumors. The kit ships as a 96 Assays pack with all reagents needed for a microplate-based run, and the colorimetric end-point is read on standard plate readers. Researchers use it to correlate PHGDH protein levels with serine pathway activity, drug response, or genetic background across cell lysates and tissue extracts. It is intended for research use only and supports studies of one-carbon metabolism, tumor biology, and neurological disorders linked to PHGDH mutations, including Neu-Laxova syndrome and infantile serine deficiency.