Human PHD finger protein 1 (PHF1) ELISA Kit

A sandwich-format ELISA Kit from Assay Genie enables quantitative detection of human PHD finger protein 1 (PHF1), a Polycomb group protein implicated in epigenetic regulation. The kit uses a colorimetric detection method and is reactive with human samples, including serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

Performance characteristics include a detection range of 0.312-20ng/mL, a sensitivity of 0.21ng/mL, an intra-assay CV of 5.2%, and an inter-assay CV of 9.7%. The assay is specific for natural and recombinant human PHF1, is designated for research use only, and is suited to work in the neurosciences.

PHF1 binds histone H3 trimethylated at Lys-36 (H3K36me3) and recruits the PRC2 complex, and is involved in the DNA damage response at double-strand breaks. It also regulates p53/TP53 stability. Dysregulation of PHF1 has been linked to cancer, neurodevelopmental disorders, and psychiatric conditions, so the kit supports research into epigenetic mechanisms and disease-relevant therapeutic targets.