Human PGRMC1 ELISA Kit (HUFI07246)

The Human PGRMC1 ELISA Kit from Assay Genie quantitatively measures Progesterone Receptor Membrane Component 1 (PGRMC1), a single-pass transmembrane protein central to non-genomic steroid hormone signaling. PGRMC1 binds progesterone and related steroids, interacts with cytochrome P450 enzymes and heme, and has been implicated in ovarian follicle maintenance, neuronal survival, and tumor cell chemoresistance in breast, ovarian, and cervical cancer models.

Researchers apply this microplate-based ELISA to profile PGRMC1 expression across studies of reproductive endocrinology, neurodegeneration, and oncology. The kit employs a human-specific capture antibody pair with a biotin-streptavidin-HRP reporter. Each kit includes pre-coated wells, lyophilized standards, biotinylated detection antibody, and substrate reagents for an enzyme-mediated signal readout. For research use only.