Human PGAM5 (Serine/threonine-protein phosphatase PGAM5, mitochondrial) ELISA KIT (HUFI04878)

Mitochondrial serine/threonine phosphatase PGAM5 plays central roles in programmed necrosis (necroptosis), mitochondrial fission dynamics, and oxidative stress responses, so quantitative measurement of this enzyme supports cell death and neurodegeneration research. This human-specific ELISA kit from Assay Genie is configured to detect endogenous PGAM5 protein in research samples from human donors, supplied as a complete 96 Assays pack with a pre-coated plate, lyophilized standards, detection antibody, and assay buffers required for a full plate run. Intended for research use only.

Researchers studying necroptosis signaling through the RIPK1/RIPK3/MLKL cascade, mitochondrial dysfunction in Parkinson's disease and ALS models, or cardiac ischemia-reperfusion injury can use this immunoassay to obtain a quantitative readout of PGAM5 protein levels for pathway dissection. The plate workflow accommodates a standard curve, blank wells, and unknown samples processed in duplicate or triplicate within a single experimental batch, supporting both targeted hypothesis testing and broader screening of mitochondrial stress responses.