Human Period Circadian Protein 1 (PER1) ELISA Kit

Quantitative chronobiology work depends on accurate measurement of the core clock gene product Period Circadian Protein 1, and this Assay Genie colorimetric ELISA kit supports that research with cell lysates and tissue homogenates from human sources as validated input matrices. PER1 forms the negative limb of the mammalian circadian oscillator, where it represses CLOCK-BMAL1-driven transcription until targeted degradation resets the roughly 24-hour cycle; tracking its abundance has become central to studies of shift-work pathophysiology, hepatic glucose handling, jet-lag recovery, glioblastoma timing, and chronopharmacology. The 96 assays kit format suits medium-throughput circadian time-course experiments across multiple tissues, donors, or treatment arms. Components include pre-coated microwell strips, a detection antibody, wash buffer, substrate, and stop solution supplied in individual vials, with a protocol insert detailing incubation times and curve-fitting recommendations. Handling guidance calls for refrigerated protection of unused reagents between runs, protection from light for substrate aliquots, and bench-side equilibration before each assay, supporting reproducible in vitro phase-shift work and in vivo circadian phenotyping in translational pipelines.