Human Pepsinogen I PharmaGenie ELISA Kit (SBRS0991)

Human pepsinogen I is a 42 kDa aspartic protease zymogen secreted by gastric chief cells, and it serves as a non-invasive serological biomarker for evaluating gastric mucosal integrity in clinical research. This Assay Genie quantitative ELISA kit enables researchers to measure pepsinogen I concentrations in cell culture supernatant, plasma, or serum specimens using a colorimetric readout. Each kit provides reagents sufficient for 96 assays in a microplate format, with components arranged for refrigerated storage to preserve immunoconjugate activity. The assay supports investigation of atrophic gastritis, H. pylori-associated gastric pathology, peptic ulcer biology, and population-level screening studies examining preneoplastic gastric lesions. Pepsinogen I levels are commonly interpreted alongside the pepsinogen I/II ratio and gastrin-17 to assess corpus atrophy and gastric cancer risk within epidemiological cohorts. All components are intended for research use only and are validated for human reactivity, making the kit suitable for translational biomarker studies in gastroenterology and gastrointestinal oncology research laboratories.