Human PCPE-1 PharmaGenie ELISA Kit (SBRS0976)

This colorimetric immunoassay from Assay Genie quantifies human Procollagen C-Proteinase Enhancer 1 (PCPE-1, also known as PCOLCE), a secreted glycoprotein of approximately 55 kDa that potentiates BMP-1 and tolloid-like proteinase activity during C-terminal procollagen processing. The kit supports research into extracellular matrix remodeling, connective tissue biology, wound healing, and tumor microenvironment studies, where PCPE-1 expression serves as a biomarker for collagen biosynthesis activity.

Cell culture supernatant, plasma, or serum samples can be analyzed, making the kit versatile for both in vitro cell-based experiments and clinical specimen work. It is supplied as a complete microplate research kit intended for research use only, providing a quantitative detection method suitable for measuring circulating PCPE-1 across diverse biological matrices.

Each kit includes pre-coated microplate wells, detection antibody, standards, and the reagents required to run the protocol. The format provides 96 assays per plate. Investigators studying cardiac fibrosis, hepatic fibrosis, keloid formation, scleroderma, osteogenesis, or dermal connective tissue development will find PCPE-1 quantification a useful complementary marker alongside hydroxyproline assays or direct type I and type III collagen measurements.