Human PCBD2 (Pterin-4-alpha-carbinolamine dehydratase 2) ELISA Kit (HUFI03446)

The PCBD2 protein, also called DCoH2, drives tetrahydrobiopterin (BH4) regeneration through pterin-4-alpha-carbinolamine dehydratase activity, supplying a cofactor needed by phenylalanine hydroxylase and nitric oxide synthase. Researchers investigating BH4 metabolism, hyperphenylalaninemia, or HNF1 transcription factor dimerization can quantify native PCBD2 in human serum with this Assay Genie ELISA kit, which is specific for the human PCBD2 isoform and covers a quantitative range of 0.156–10 ng/mL with a sensitivity around 0.05 ng/mL. Reagents supplied include pre-coated microplate strips, lyophilized standards, biotinylated detection antibody, and horseradish peroxidase substrate for in vitro quantitative work. Unopened kits should be stored at 4 degrees C and protected from light; reconstituted standards and detection antibody are best aliquoted into single-use vials to limit freeze-thaw cycles.