Human Parathyroid hormone-related protein (PTHLH) ELISA Kit

PTHrP is a key regulatory protein with vital roles in bone development, calcium homeostasis, and cancer progression. Its dysregulation has been linked to skeletal diseases, hypercalcemia, and various malignancies, making it an important biomarker for research. The Assay Genie ELISA kit is designed for the accurate measurement of PTHrP levels in human samples such as serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, supporting investigations in bone metabolism, cancer biology, and endocrine disorders.

Configured as a competitive ELISA, the assay has a detection range of 15.6-1000 pg/mL and a sensitivity of 4.9 pg/mL. Intra-assay CV is 4.3% and inter-assay CV is 6.9%. Linearity is reported for serum, EDTA plasma, and heparin plasma at dilutions of 1:2, 1:4, 1:8, and 1:16, with recovery averaging 100% (94-106%) in serum and 102% (96-108%) in plasma. Specificity is directed toward natural and recombinant human Parathyroid hormone-related protein.

Synonyms for the target include Parathyroid hormone-like protein, PLP, PTH-rP, and PTHRP. The kit is intended for research use only, and is relevant to cancer research as well as to the study of osteostatin, a potent inhibitor of osteoclastic bone resorption. The target protein is catalogued under UniProt P12272.