Human Pannexin-1 (PANX1) ELISA Kit

Assay Genie offers a Sandwich ELISA Kit for the quantitative measurement of human Pannexin-1 (PANX1) levels in biological samples. The kit is intended for research use only and supports studies where pannexin-1 acts as a biomarker of interest, including investigations into inflammation, neurological disorders, and cardiovascular disease.

Performance characteristics include a detection range of 0.156–10 ng/mL, a sensitivity of 0.078 ng/mL, an intra-assay CV of 4.6%, and an inter-assay CV of 8.3%. Specificity has been established for both natural and recombinant human Pannexin-1, and reactivity is limited to human samples.

Validated sample types include serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. The listed research area is cancer, and pannexin-1 is described as a structural component of gap junctions and hemichannels, potentially acting as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.