Human Oxysterols receptor LXR-alpha (NR1H3) ELISA Kit

Designed for quantitative measurement of human oxysterols receptor LXR-alpha (NR1H3), this sandwich ELISA from Assay Genie offers a reliable tool for research into lipid metabolism and related metabolic disorders. The kit is intended for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and detects both natural and recombinant human LXR-alpha.

The assay provides a detection range of 0.312–20 ng/mL with a sensitivity of 0.078 ng/mL. Intra-assay precision is reported at a CV of 6.2% and inter-assay precision at 11.2%. Linearity across 1:2 to 1:16 dilutions spans 87–115% for serum, 91–121% for EDTA plasma, and 91–117% for heparin plasma. Average recovery is 111% (range 105–117%) in serum and 113% (range 107–119%) in plasma.

LXR-alpha, also referred to as Liver X receptor alpha, Nuclear receptor subfamily 1 group H member 3, or LXRA, is a nuclear receptor central to cholesterol homeostasis and inflammatory control, positioning it as a relevant biomarker for cardiovascular research. The product is for research use only.