Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) ELISA Kit

The Assay Genie OSGIN1 ELISA Kit enables quantitative measurement of oxidative stress-induced growth inhibitor 1, a ~30 kDa protein also known as OKL38 that is upregulated by hydrogen peroxide and other reactive oxygen species. OSGIN1 acts as a tumor suppressor by linking redox imbalance to growth arrest and apoptotic signaling in transformed cells.

This immunoassay supports research into hepatocellular carcinoma, lung adenocarcinoma, and the Nrf2 antioxidant response pathway, where altered OSGIN1 expression has been documented in tumor versus matched normal tissue. The kit is calibrated for tissue homogenates and cell lysates, with a human-specific antibody pair that does not cross-react with rodent homologs.

All kit components should be kept refrigerated; standards should be aliquoted to limit repeated freeze-thaw events. The microplate format provides enough reagents for 96 tests, suiting medium-throughput studies on redox biology, chemoprevention, and stress-induced apoptosis in human cell or tissue models.